2. Academic Validation
  3. Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors

Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors

  • Chem Commun (Camb). 2006 Feb 14;(6):629-31. doi: 10.1039/b514915k.
Kai-Hsuan Chang 1,  Lenselot Lee,  Jessica Chen,  Wen-Shan Li
Affiliations

Affiliation

  • 1 Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan.
PMID: 16446832 DOI: 10.1039/b514915k
Abstract

A new type of noncompetitive alpha-2,3-sialyltransferase inhibitor has been synthesized; we report the discovery, preparation and inhibitory activity of sixteen lithocholic acid analogues.

Figures
Products