1. Academic Validation
  2. Preclinical and clinical evaluation of recombinant human macrophage colony-stimulating factor (rhM-CSF)

Preclinical and clinical evaluation of recombinant human macrophage colony-stimulating factor (rhM-CSF)

  • Int J Cell Cloning. 1990 Jan;8 Suppl 1:356-71; discussion 371-3. doi: 10.1002/stem.5530080733.
M B Garnick 1 J B Stoudemire
Affiliations

Affiliation

  • 1 Genetics Institute, Cambridge, Massachusetts 02140.
Abstract

The promise of hematopoietic growth factors is now being realized as clinical trials become more mature. The uses of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor are now becoming more established in therapeutic applications of disease states. A variety of new hematopoietic growth factors is on the horizon, including recombinant human macrophage colony-stimulating factor (rhM-CSF), which has recently entered clinical trials after extensive preclinical testing. The diverse biological actions of rhM-CSF will provide novel ways of approaching various medical problems across the disciplines of hematology, oncology, infectious disease and cardiology.

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