2. Academic Validation
  3. Lignans from Schisandra propinqua with inhibitory effects on lymphocyte proliferation

Lignans from Schisandra propinqua with inhibitory effects on lymphocyte proliferation

  • Planta Med. 2012 May;78(8):807-13. doi: 10.1055/s-0031-1298439.
Mei Na Jin 1,  Zhi Yao,  Yoshihisa Takaishi,  Hong Quan Duan
Affiliations

Affiliation

  • 1 School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
PMID: 22499561 DOI: 10.1055/s-0031-1298439
Abstract

Seven new dibenzocyclooctadiene Lignans, named propinquain E-K, together with 11 known Lignans were isolated from the ethanol extract of the roots of Schisandra propinqua subsp. sinensis. The structures of the new compounds were elucidated by spectroscopic methods, including ¹H- and ¹³C-NMR, 2D-NMR, HR ESI-MS, and CD spectra. Two dibenzocyclooctadienes revealed inhibitory effects on lymphocyte proliferation.

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