2. Academic Validation
  3. Two new natural azafluorene alkaloids and a cytotoxic aporphine alkaloid from Polyalthia longifolia

Two new natural azafluorene alkaloids and a cytotoxic aporphine alkaloid from Polyalthia longifolia

  • J Nat Prod. 1990 Sep-Oct;53(5):1327-31. doi: 10.1021/np50071a028.
Y C Wu 1,  C Y Duh,  S K Wang,  K S Chen,  T H Yang
Affiliations

Affiliation

  • 1 School of Pharmacy, Kaohsiung Medical College, Taiwan, Republic of China.
PMID: 2292689 DOI: 10.1021/np50071a028
Abstract

The stem and stem bark of Polyalthia longifolia afforded the cytotoxic aporphine alkaloid liriodenine [1], as well as two Aporphine Alkaloids, noroliveroline [2] and oliveroline-beta-N-oxide [3] and three azafluorene Alkaloids, darienine [4], polyfothine [6], and isooncodine [7], which are not bioactive. Polyfothine [6] and isooncodine [7] are new natural compounds.

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