2. Academic Validation
  3. The cyclic AMP pathway

The cyclic AMP pathway

  • Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148. doi: 10.1101/cshperspect.a011148.
Paolo Sassone-Corsi 1
Affiliations

Affiliation

  • 1 Center for Epigenetics and Metabolism, School of Medicine, University of California, Irvine, CA 92697, USA. [email protected]
PMID: 23209152 DOI: 10.1101/cshperspect.a011148
Abstract

cAMP was the first second messenger to be identified. Its three main effectors are PKA (which phosphorylates numerous metabolic enzymes), EPAC (a guanine-nucleotide-exchange factor), and cyclic-nucleotide-gated ion channels.

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