2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Cyclic AMP

Cyclic AMP  (Synonyms: Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP)

Cat. No.: HY-B1511 Purity: 99.94%
COA Handling Instructions

Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes.

For research use only. We do not sell to patients.

Cyclic AMP Chemical Structure

Cyclic AMP Chemical Structure

CAS No. : 60-92-4

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Based on 4 publication(s) in Google Scholar

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Description

Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

Microbial Metabolite

 

In Vitro

Cyclic AMP (Cyclic adenosine monophosphate) modulates mediator generation. Cyclic AMP suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

329.21

Appearance

Solid

Formula

C10H12N5O6P
CAS No.
SMILES

NC1=C2N=CN([[email protected]@H]3O[[email protected]]4([H])COP(O)(O[[email protected]@]4([H])[[email protected]]3O)=O)C2=NC=N1
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

0.1 M NaOH : 30 mg/mL (91.13 mM; ultrasonic and adjust pH to 6 with NaOH)

H2O : 2.4 mg/mL (7.29 mM; Need ultrasonic)

DMSO : 1 mg/mL (3.04 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0376 mL 15.1879 mL 30.3757 mL
5 mM 0.6075 mL 3.0376 mL 6.0751 mL
10 mM 0.3038 mL 1.5188 mL 3.0376 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.94%

COA (255 KB) HNMR (123 KB) LCMS (109 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cyclic AMP60-92-4Cyclic adenosine monophosphate Adenosine cyclic 3', 5'-monophosphate cAMPEndogenous Metabolitesecond messengerbiological processesderivativeadenosine triphosphatesignal transductionInhibitorinhibitorinhibit

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