2. Academic Validation
  3. ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying Lymphoid Tumorigenesis

ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying Lymphoid Tumorigenesis

Thomas Bannister 1,  Marcel Koenig 1,  Yuanjun He 1,  Jitendra Mishra 1,  Tim Spicer 2,  Dmitriy Minond 2,  Adrian Saldanha 2,  Becky A. Mercer 2,  Michael Cameron 3,  Ryan Lena 4,  Nicole Carlson 4,  David Richard 4,  Michael Cardone 4,  Peter Hodder 2 3
Affiliations

Affiliations

  • 1 The Scripps Research Institute, Departments of Chemistry and Translational Res., Jupiter, FL
  • 2 The Scripps Research Institute, Lead Identification Division, Jupiter, FL
  • 3 The Scripps Research Institute, Department of Molecular Therapeutics, Jupiter, FL
  • 4 Eutropics Pharmaceuticals, Cambridge, MA
PMID: 23762927
Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-101778
    98.26%, Bcl-2 Family Inhibitor