2. Academic Validation
  3. Potential Health Benefits of Olive Oil and Plant Polyphenols

Potential Health Benefits of Olive Oil and Plant Polyphenols

  • Int J Mol Sci. 2018 Feb 28;19(3):686. doi: 10.3390/ijms19030686.
Monika Gorzynik-Debicka 1,  Paulina Przychodzen 2,  Francesco Cappello 3 4,  Alicja Kuban-Jankowska 5,  Antonella Marino Gammazza 6 7,  Narcyz Knap 8,  Michal Wozniak 9,  Magdalena Gorska-Ponikowska 10 11
Affiliations

Affiliations

  • 1 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 2 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 3 Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. [email protected].
  • 4 Euro-Mediterranean Institute of Science and Technology (IEMEST), 90136 Palermo, Italy. [email protected].
  • 5 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 6 Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. [email protected].
  • 7 Euro-Mediterranean Institute of Science and Technology (IEMEST), 90136 Palermo, Italy. [email protected].
  • 8 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 9 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 10 Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. [email protected].
  • 11 Institute of Biomaterials and Biomolecular Systems, Department of Biophysics, University of Stuttgart, 70569 Stuttgart, Germany. [email protected].
PMID: 29495598 DOI: 10.3390/ijms19030686
Abstract

Beneficial effects of natural plant Polyphenols on the human body have been evaluated in a number of scientific research projects. Bioactive Polyphenols are natural compounds of various chemical structures. Their sources are mostly fruits, vegetables, nuts and seeds, roots, bark, leaves of different Plants, herbs, whole grain products, processed foods (dark chocolate), as well as tea, coffee, and red wine. Polyphenols are believed to reduce morbidity and/or slow down the development of cardiovascular and neurodegenerative diseases as well as Cancer. Biological activity of Polyphenols is strongly related to their antioxidant properties. They tend to reduce the pool of Reactive Oxygen Species as well as to neutralize potentially carcinogenic metabolites. A broad spectrum of health-promoting properties of plant Polyphenols comprises antioxidant, anti-inflammatory, anti-allergic, anti-atherogenic, anti-thrombotic, and anti-mutagenic effects. Scientific studies present the ability of Polyphenols to modulate the human immune system by affecting the proliferation of white blood cells, and also the production of cytokines or other factors that participate in the immunological defense. The aim of the review is to focus on Polyphenols of olive oil in context of their biological activities.

Keywords

Olea europea; anticancer therapy; hydroxytyrosol; oleuropein; olive oil; polyphenols.

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