2. Academic Validation
  3. In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

  • Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241.
Montserrat Pérez-Salvia 1,  Eneko Aldaba 2,  Yosu Vara 2,  Myriam Fabre 3,  Cristina Ferrer 3,  Carme Masdeu 4,  Aizpea Zubia 5,  Eider San Sebastian 5,  Dorleta Otaegui 6,  Pere Llinàs-Arias 1,  Margalida Rosselló-Tortella 1,  Maria Berdasco 1,  Catia Moutinho 1,  Fernando Setien 1,  Alberto Villanueva 7,  Eva González-Barca 8,  Josep Muncunill 9,  José-Tomás Navarro 9,  Miguel A Piris 10,  Fernando P Cossio 5,  Manel Esteller 11 12 13 14
Affiliations

Affiliations

  • 1 Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL) L'Hospitalet, Barcelona, Catalonia.
  • 2 Quimatryx, San Sebastian.
  • 3 Oncomatryx, Arteaga Auzoa, 43, Derio.
  • 4 Department of Organic Chemistry I, Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), San Sebastián.
  • 5 Department of Organic Chemistry I, Centro de Innovación en Química Avanzada (ORFEO-CINQA), Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Donostia International Physics Center (DIPC), San Sebastián.
  • 6 Mass Spectrometry Platform, CIC biomaGUNE, San Sebastian.
  • 7 Laboratory of Translational Research, Catalan Institute of Oncology (ICO), IDIBELL L'Hospitalet, Barcelona, Catalonia.
  • 8 Department of Hematology, ICO-Hospital Duran i Reynals, IDIBELL, University of Barcelona, L'Hospitalet, Barcelona, Catalonia.
  • 9 Department of Hematology, ICO-Hospital Universitari Germans Trias i Pujol, Josep Carreras Leukaemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Catalonia.
  • 10 Pathology Service, Fundación Jiménez Díaz, Madrid.
  • 11 Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL) L'Hospitalet, Barcelona, Catalonia [email protected].
  • 12 Centro de Investigacion Biomedica en Red Cancer (CIBERONC), Madrid.
  • 13 Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), L'Hospitalet, Catalonia.
  • 14 Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.
PMID: 29880608 DOI: 10.3324/haematol.2018.189241
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