2. Academic Validation
  3. Preliminary analysis of the chemical composition, antioxidant and anticholinesterase activities of Algerian propolis

Preliminary analysis of the chemical composition, antioxidant and anticholinesterase activities of Algerian propolis

  • Nat Prod Res. 2020 Nov;34(22):3257-3261. doi: 10.1080/14786419.2018.1556658.
Amina Bouaroura 1,  Narimane Segueni 1,  Jesus G Diaz 2,  Chawki Bensouici 3,  Salah Akkal 4,  Salah Rhouati 1
Affiliations

Affiliations

  • 1 Laboratory of Natural Product and Organic Synthesis, Department of Chemistry, Univesity Constantine 1, Constantine, Algeria.
  • 2 Departamento de Química Orgánica, Instituto Universitario de Bio-orgánica "Antonio Gonzalez" Universidad de La Laguna, La Laguna, Spain.
  • 3 Centre de Recherche en Biotechnologie, Constantine, Algeria.
  • 4 Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine1, Constantine, Algeria.
PMID: 30760045 DOI: 10.1080/14786419.2018.1556658
Abstract

Many studies demonstrated that Algerian propolis possess a large spectrum of biological activity. However, few studies regarding its chemical composition are available on literature. We aimed in the present study to investigate the chemical composition of Algerian propolis. In addition, the Antioxidants and anticholinesterase activities of propolis extracts are also reported. Chemical investigation of Algerian propolis allowed the isolation of 8 compounds. Their structures were identified on the basis of spectral data and comparison with literature. The isolated compounds are considered as markers of poplar and Citrus spp suggesting the use of both species as plant source of the tested propolis. The ethyl acetate extract of the tested propolis demonstrated the highest antioxidant activity. Among the tested extracts, only the petroleum ether and chloroform extracts exhibited an AChE inhibitory activity.

Keywords

Algerian propolis; anticholinesterase activity; antioxidant activity; chemical composition.

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