2-Methyl-2-butenyl (E)-Caffeate
2-Methyl-2-butenyl (E)-Caffeate is a type of caffeic acid ester compound. The petroleum ether and chloroform extracts containing 2-Methyl-2-butenyl (E)-Caffeate have inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The ether extract containing 2-Methyl-2-butenyl (E)-Caffeate exhibits strong antioxidant properties. 2-Methyl-2-butenyl (E)-Caffeate can be used in the research of Alzheimer's disease.
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- CAS. Nr.: 118971-61-2
- Formel: C14H16O4
- Molecular Weight:248.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
AChE |
BChE |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| RAW264.7 | EC50 |
0.578 μM
Compound: 20, prenyl caffeate
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Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation administered 1 hr before LPS challenge and measured after 24 hrs by Griess reagent assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation administered 1 hr before LPS challenge and measured after 24 hrs by Griess reagent assay
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[PMID: 18667320] |
| RAW264.7 | EC50 |
30 μM
Compound: 20, prenyl caffeate
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Cytotoxicity against mouse RAW264.7 cells assessed as cell survival after 24 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as cell survival after 24 hrs by MTT assay
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[PMID: 18667320] |
Chemical Information
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CAS. Nr. 118971-61-2
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Molecular Weight 248.27
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Formel C14H16O4
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SMILES
C/C(C)=C\COC(/C=C/C1=CC(O)=C(C=C1)O)=O
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Structure Classification
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Initial Source
Algerian propolis
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
2-Methyl-2-butenyl (E)-Caffeate Related Classifications
HY-W746884 Related Classifications
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