2. Academic Validation
  3. Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders

Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders

  • Molecules. 2022 Feb 24;27(5):1539. doi: 10.3390/molecules27051539.
Saurabh Bhatia 1 2,  Rashita Makkar 3,  Tapan Behl 3,  Aayush Sehgal 3,  Sukhbir Singh 3,  Mahesh Rachamalla 4,  Vasudevan Mani 5,  Muhammad Shahid Iqbal 6,  Simona Gabriela Bungau 7 8
Affiliations

Affiliations

  • 1 Natural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz 616, Nizwa P.O. Box 33, Oman.
  • 2 School of Health Science, University of Petroleum and Energy Studies, Dehradun 248007, India.
  • 3 Chitkara College of Pharmacy, Chitkara University, Patiala 140401, India.
  • 4 Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, SK S7N 5E2, Canada.
  • 5 Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah 51452, Saudi Arabia.
  • 6 Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
  • 7 Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
  • 8 Doctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
PMID: 35268639 DOI: 10.3390/molecules27051539
Abstract

Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as Cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches.

Keywords

cancer; cardiovascular disorders; diabetes mellitus; marine drugs; neurodegeneration.

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