Metubine  (Synonyms: Metocurine iodide; Dimethylchondrocurarine iodide)

Metubine (Metocurine iodide) is a non-depolarizing muscle relaxant. Metubine has neuromuscular blocking activities^[1][2].

Metubine (>15.0×10^-3 g/L) produces dose-dependent decreases in the isometric force (F) and the maximum velocity of force development (dF/dt) in isolated canine heart muscle^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

906.63

C₄₀H₄₈I₂N₂O₆

7601-55-0

COC(C(OC1=CC=C(C[C@@]([N+](C)(CC2)C)([H])C3=C2C=C(OC)C4=C3)C=C1)=C5[C@@]6([H])CC7=CC=C(OC)C(O4)=C7)=C(C=C5CC[N+]6(C)C)OC.[I-].[I-]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Iwatsuki N, et al. Inotropic effects of non-depolarizing muscle relaxants in isolated canine heart muscle. Anesth Analg. 1980 Oct;59(10):717-21.  [Content Brief]

  [2]. Durant NN, et al. A comparison of the neuromuscular and autonomic blocking activities of (+)-tubocurarine and its N-methyl and O,O,N-trimethyl analogues. Eur J Pharmacol. 1977 Dec 15;46(4):297-302.  [Content Brief]