Myelin Basic Protein (1-11) 

Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)^[1][2].

Myelin Basic Protein (1-11) (0-10 μg/mL) stimulates IL-2 production in MBP-TCR CD4 T cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC cells (i.p.) leads to experimental autoimmune encephalomyelitis (EAE) when transferred into irradiated B10.PL mice^[1].
Myelin Basic Protein (1-11) (100 μg, i.p.) induced tolerance to MBP in adult mice and prevents MBP-induced EAE^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1293.39

C₅₂H₈₈N₂₂O₁₇

106128-98-7

Ac-ASQKRPSQRHG

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9.  [Content Brief]

  [2]. Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4.  [Content Brief]