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N,N'-Carbonyldiimidazole  (Synonyms: 1,1'-Carbonyldiimidazole)

Art. -Nr.: HY-79880 Reinheit: 99.9%
Handling Instructions Technical Support

N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent.

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N,N'-Carbonyldiimidazole

N,N'-Carbonyldiimidazole Chemische Struktur

CAS. Nr. : 530-62-1

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
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Beschreibung

N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent[1][2][3].

In Vitro

N,N'-Carbonyldiimidazole is a highly reactive reagent that can mediate the conjugation of ovalbumin with magnetite nanoparticles for vaccine delivery[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

162.15

Formel

C7H6N4O

CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C=NC=C1)N2C=NC=C2

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

RT, protect from light, stored under nitrogen

In solvent -80°C 1 year
-20°C 6 months
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : ≥ 100 mg/mL (616.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.1671 mL 30.8356 mL 61.6713 mL
5 mM 1.2334 mL 6.1671 mL 12.3343 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.9%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.1671 mL 30.8356 mL 61.6713 mL 154.1782 mL
5 mM 1.2334 mL 6.1671 mL 12.3343 mL 30.8356 mL
10 mM 0.6167 mL 3.0836 mL 6.1671 mL 15.4178 mL
15 mM 0.4111 mL 2.0557 mL 4.1114 mL 10.2785 mL
20 mM 0.3084 mL 1.5418 mL 3.0836 mL 7.7089 mL
25 mM 0.2467 mL 1.2334 mL 2.4669 mL 6.1671 mL
30 mM 0.2056 mL 1.0279 mL 2.0557 mL 5.1393 mL
40 mM 0.1542 mL 0.7709 mL 1.5418 mL 3.8545 mL
50 mM 0.1233 mL 0.6167 mL 1.2334 mL 3.0836 mL
60 mM 0.1028 mL 0.5139 mL 1.0279 mL 2.5696 mL
80 mM 0.0771 mL 0.3854 mL 0.7709 mL 1.9272 mL
100 mM 0.0617 mL 0.3084 mL 0.6167 mL 1.5418 mL
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N,N'-Carbonyldiimidazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N,N'-Carbonyldiimidazole
Art. -Nr.:
HY-79880
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