1. Cell Cycle/DNA Damage
  2. DNA Alkylator/Crosslinker
  3. N-Succinimidyl 4-[4-maleimidophenyl]butyrate

N-Succinimidyl 4-[4-maleimidophenyl]butyrate 

Cat. No.: HY-W011123 Purity: 98.0%
Handling Instructions Technical Support

N-Succinimidyl 4-[4-maleimidophenyl]butyrate is a crosslinking agent.

For research use only. We do not sell to patients.

N-Succinimidyl 4-[4-maleimidophenyl]butyrate

N-Succinimidyl 4-[4-maleimidophenyl]butyrate Chemical Structure

CAS No. : 79886-55-8

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Description

N-Succinimidyl 4-[4-maleimidophenyl]butyrate is a crosslinking agent.

Molecular Weight

356.33

Formula

C18H16N2O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(ON1C(CCC1=O)=O)CCCC2=CC=C(N3C(C=CC3=O)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (280.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8064 mL 14.0319 mL 28.0639 mL
5 mM 0.5613 mL 2.8064 mL 5.6128 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8064 mL 14.0319 mL 28.0639 mL 70.1597 mL
5 mM 0.5613 mL 2.8064 mL 5.6128 mL 14.0319 mL
10 mM 0.2806 mL 1.4032 mL 2.8064 mL 7.0160 mL
15 mM 0.1871 mL 0.9355 mL 1.8709 mL 4.6773 mL
20 mM 0.1403 mL 0.7016 mL 1.4032 mL 3.5080 mL
25 mM 0.1123 mL 0.5613 mL 1.1226 mL 2.8064 mL
30 mM 0.0935 mL 0.4677 mL 0.9355 mL 2.3387 mL
40 mM 0.0702 mL 0.3508 mL 0.7016 mL 1.7540 mL
50 mM 0.0561 mL 0.2806 mL 0.5613 mL 1.4032 mL
60 mM 0.0468 mL 0.2339 mL 0.4677 mL 1.1693 mL
80 mM 0.0351 mL 0.1754 mL 0.3508 mL 0.8770 mL
100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.7016 mL
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N-Succinimidyl 4-[4-maleimidophenyl]butyrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N-Succinimidyl 4-[4-maleimidophenyl]butyrate
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