1. PROTAC Epigenetics
  2. Ligands for Target Protein for PROTAC WDR5
  3. OICR-9429-N-C2-NH2

OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs.

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OICR-9429-N-C2-NH2

OICR-9429-N-C2-NH2 화학구조

CAS No. : 2407457-55-8

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제품 설명

OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs[1].

IC50 & Target

Ligand for Target Protein for PROTAC[1]

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

597.67

화학식

C31H38F3N7O2

CAS No.
SMILES

CN(CC1)CCN1C(C(NC(C2=CNC(C=C2C(F)(F)F)=O)=O)=C3)=CC=C3C4=CC(CN5CCN(CCN)CC5)=CC=C4

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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상품명:
OICR-9429-N-C2-NH2
Cat. No.:
HY-141798
수량:
MCE Japan Authorized Agent: