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  3. Piperazin-2-one

Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds.

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Piperazin-2-one

Piperazin-2-one Chemische Struktur

CAS. Nr. : 5625-67-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
25 g Auf Lager
100 g Auf Lager
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Beschreibung

Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds[1][2][3].

In Vitro

Piperazin-2-one derivatives exhibit anti-adenoviral activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

100.12

Formel

C4H8N2O

CAS. Nr.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NCCNC1

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (998.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.9880 mL 49.9401 mL 99.8801 mL
5 mM 1.9976 mL 9.9880 mL 19.9760 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.97%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 9.9880 mL 49.9401 mL 99.8801 mL 249.7004 mL
5 mM 1.9976 mL 9.9880 mL 19.9760 mL 49.9401 mL
10 mM 0.9988 mL 4.9940 mL 9.9880 mL 24.9700 mL
15 mM 0.6659 mL 3.3293 mL 6.6587 mL 16.6467 mL
20 mM 0.4994 mL 2.4970 mL 4.9940 mL 12.4850 mL
25 mM 0.3995 mL 1.9976 mL 3.9952 mL 9.9880 mL
30 mM 0.3329 mL 1.6647 mL 3.3293 mL 8.3233 mL
40 mM 0.2497 mL 1.2485 mL 2.4970 mL 6.2425 mL
50 mM 0.1998 mL 0.9988 mL 1.9976 mL 4.9940 mL
60 mM 0.1665 mL 0.8323 mL 1.6647 mL 4.1617 mL
80 mM 0.1249 mL 0.6243 mL 1.2485 mL 3.1213 mL
100 mM 0.0999 mL 0.4994 mL 0.9988 mL 2.4970 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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