Pyrogallol-phloroglucinol-6,6-bieckol

Name: Pyrogallol-phloroglucinol-6,6-bieckol
Brand: MedChemExpress
SKU: HY-N11729
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Cat. No.: HY-N11729 Pureté: 80.0%: Fiche technique
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Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia.

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Pyrogallol-phloroglucinol-6,6-bieckol Chemical Structure

CAS No. : 1415504-32-3

Size	Stock	Quantité
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtenir un devis
100 mg	Obtenir un devis

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Description

Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia^[1].

Masse moléculaire

974.74

Formule

C₄₈H₃₀O₂₃

CAS No.

1415504-32-3

Appearance

Solid

Color

Light yellow to brown

SMILES

OC1=CC(OC2=C(C=C(C=C2O)OC3=CC(O)=CC(OC4=C(C=C(C(OC5=C(C6=C(C=C(C7=C6OC8=C(C(OC9=CC(O)=CC(O)=C9)=C(C=C8O)O)O7)O)O)C(O)=C%10)=C4OC5=C%10O)O)O)=C3)O)=CC(O)=C1

Structure Classification

Initial Source

Microorganisms

Ecklonia cava

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvant et solubilité

In Vitro:

DMSO : 100 mg/mL (102.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0259 mL	5.1296 mL	10.2591 mL
5 mM	0.2052 mL	1.0259 mL	2.0518 mL
10 mM	0.1026 mL	0.5130 mL	1.0259 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (2.56 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Pureté et documentation

Purity: 80.0%

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Fiche technique (271 KB) SDS (251 KB)

COA (252 KB) HNMR (334 KB) LCMS (94 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Lee JH, et al. Preparative isolation and purification of phlorotannins from Ecklonia cava using centrifugal partition chromatography by one-step. Food Chem. 2014 Sep 1;158:433-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0259 mL	5.1296 mL	10.2591 mL	25.6479 mL
	5 mM	0.2052 mL	1.0259 mL	2.0518 mL	5.1296 mL
	10 mM	0.1026 mL	0.5130 mL	1.0259 mL	2.5648 mL
	15 mM	0.0684 mL	0.3420 mL	0.6839 mL	1.7099 mL
	20 mM	0.0513 mL	0.2565 mL	0.5130 mL	1.2824 mL
	25 mM	0.0410 mL	0.2052 mL	0.4104 mL	1.0259 mL
	30 mM	0.0342 mL	0.1710 mL	0.3420 mL	0.8549 mL
	40 mM	0.0256 mL	0.1282 mL	0.2565 mL	0.6412 mL
	50 mM	0.0205 mL	0.1026 mL	0.2052 mL	0.5130 mL
	60 mM	0.0171 mL	0.0855 mL	0.1710 mL	0.4275 mL
	80 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.3206 mL
	100 mM	0.0103 mL	0.0513 mL	0.1026 mL	0.2565 mL