Immune Checkpoint Proteins

ICPs have been identified and studied in cancer, including PD-1, CTLA-4, LAG3 and TIGIT, etc. MedChemExpress (MCE) offers recombinant proteins, specific small molecule inhibitors/agonists, and antibody inhibitors for immune checkpoint research.

SARS-CoV-2

SARS-CoV is a positive-stranded RNA virus belonging to the family Coronaviridae. The SARS-COV-2 genome encodes at least sixteen non-structural proteins and four structural proteins.

Stem Cell Related Research

Stem cells are able to differentiate into different types of cells in the body and have unique abilities to self-renew and recreate functional tissues. MedChemExpress (MCE) offers a range of products related to stem cell culture.

Matrix Metalloproteinases

MMPs are widely involved in a variety of physiological and pathological processes, and plays an important role in cell migration, tissue remodeling, etc. MMPs have emerged as significant biomarkers and therapeutic targets in clinical diagnostics and treatment.

Cytokines for Immune Cell Culture

Immune cell culture models are essential tools in immunology research. MCE can provide a range of high-quality cytokines for the in vitro culture, activation, and differentiation of various immune cells, to enhance the controllability and reproducibility of immune cell cultures.

Neuroscience Proteins

Neuroscience is the study of the nervous system, its functions, and disorders, providing insights for improving human health. MCE offers high-quality recombinant proteins, peptides, antibodies, and kits to empower breakthroughs in neuroscience.

Angiogenesis

Angiogenesis is essential not only for physiological conditions such astissue growth and repair but also for pathological conditions such as tumor progression and survival. MCE can provide a range of high-quality recombinant proteins related to angiogenesis research.

Tumor Microenvironment

The tumor microenvironment (TME) is a dynamic ecosystem that drives tumor progression, immune evasion, and therapy resistance. Its key components—immunosuppression, metabolic reprogramming, and ECM barriers—are prime targets for precision strategies.

Attachment Factors

Attachment factors facilitate cell adhesion to culture substrates by mimicking the in vivo microenvironment. MCE offers high-quality attachment factor products designed to enhance cell adhesion and promote cell growth and functional expression in vitro.

TNF Superfamily

The tumor necrosis factor (TNF) superfamily consists of immune-related proteins that regulate diverse cellular functions and are linked to autoimmune, inflammatory diseases, and cancer. Its members are key targets in drug development, especially in tumor immunotherapy.

ADC Targets in Oncology

Antibody-drug conjugates (ADCs) are characterized to have highly specific targeting ability and potent killing effect, making them a crucial breakthrough in cancer therapy. MCE offers a full range of related products including ADC molecules and antibodies, target antigen.