BAFFR/TNFRSF13C Protein, Mouse (Biotinylated, HEK293, Fc-Avi)

BAFFR/TNFRSF13C Protein, a B-cell receptor for TNFSF13B/BAFF/BLyS, crucially supports mature B-cell survival and the overall B-cell response. Engaging with TNFSF13B, BAFFR regulates B-cell viability, ensuring the persistence of mature B-cells for an effective immune response. BAFFR/TNFRSF13C Protein, Mouse (Biotinylated, HEK293, Fc-Avi) is the recombinant mouse-derived BAFFR/TNFRSF13C protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

BAFFR/TNFRSF13C, a B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS, plays a crucial role in the survival of mature B-cells and the overall B-cell response. This receptor is instrumental in mediating the effects of the TNFSF13B ligand, also known as B-cell activating factor (BAFF) or B lymphocyte stimulator (BLyS). By engaging with TNFSF13B, BAFFR contributes to the regulation of B-cell viability, ensuring the persistence of mature B-cells and facilitating an effective B-cell immune response.

Immobilized Mouse BAFF mFc at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse BAFFR Fc-Avi with a linear range of 0.8-13 ng/mL.

Mouse

HEK293

C-Avi;C-hFc

Q9D8D0-1 (S10-A71)

72049  [NCBI]

Partial

Biotin

SQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVA

Approximately 45-60 kDa under reduced (R) conditions, 90-116 kDa under non reducing (N) conditions, based on SDS-PAGE, due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized a 0.22 μm filtered solution of 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5 with 10% trehalose as protectant.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

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It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.