1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. LI-Cadherin/Cadherin-17
  6. Cadherin-17 Protein, Cynomolgus (HEK293, Fc)

Cadherin-17 Protein, Cynomolgus (HEK293, Fc)

Cat. No.: HY-P77309
Handling Instructions

Cadherin-17 Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. Employing preferential homophilic interactions, Cadherin-17 facilitates self-binding between connecting cells. With its calcium-dependent adhesion properties, Cadherin-17 actively participates in establishing selective connections between cells, influencing the dynamic regulation of cellular interactions and contributing to the overall structural integrity of tissues, particularly in the liver and intestine. Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is 787 a.a., with molecular weight of ~111.8 KDa.

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Description

Cadherin-17 Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. Employing preferential homophilic interactions, Cadherin-17 facilitates self-binding between connecting cells. With its calcium-dependent adhesion properties, Cadherin-17 actively participates in establishing selective connections between cells, influencing the dynamic regulation of cellular interactions and contributing to the overall structural integrity of tissues, particularly in the liver and intestine. Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is 787 a.a., with molecular weight of ~111.8 KDa.

Background

Cadherin-17, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. Employing preferential homophilic interactions, Cadherin-17 facilitates self-binding between connecting cells. This homophilic cadherin engagement underscores its significance in cell adhesion and suggests a substantial contribution to the intricate process of sorting heterogeneous cell types. Additionally, Cadherin-17, also known as LI-cadherin, may play a role in the morphological organization of the liver and intestine, indicating its involvement in the structural organization of these tissues. With its calcium-dependent adhesion properties, Cadherin-17 actively participates in establishing selective connections between cells, influencing the dynamic regulation of cellular interactions and contributing to the overall structural integrity of tissues, particularly in the liver and intestine[1].

Species

Cynomolgus

Source

HEK293

Tag

C-hFc

Accession

XP_005563762 (M1-M787)

Gene ID

102129651  [NCBI]

Molecular Construction
N-term
Cadherin-17 (M1-M787)
Accession # XP_005563762
hFc
C-term
Synonyms
Cadherin-17; CDH17; Intestinal Peptide-Associated Transporter HPT-1
Molecular Weight

Approximately 111.8 kDa.

Purity

Greater than 85% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Cadherin-17 Protein, Cynomolgus (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Cadherin-17 Protein, Cynomolgus (HEK293, Fc)
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HY-P77309
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