Cadherin-6/KCAD Protein, Rat (HEK293, His)

Cadherin-6/KCAD Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. It exhibits a preference for interacting with other cadherin molecules of the same type in a homophilic manner, facilitating the adhesion between connecting cells. As a calcium-dependent adhesion protein, Cadherin-6/KCAD participates in maintaining the structural integrity of tissues and regulating cellular processes such as development, differentiation, and morphogenesis. Cadherin-6/KCAD Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Rat (HEK293, His) is 597 a.a., with molecular weight of ~67.9 KDa.

Cadherin-6/KCAD, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. It exhibits a preference for interacting with other cadherin molecules of the same type in a homophilic manner, facilitating the adhesion between connecting cells. This unique ability of cadherins to selectively interact with themselves contributes to the sorting and organization of heterogeneous cell types in tissues and organs. As a calcium-dependent adhesion protein, Cadherin-6/KCAD participates in maintaining the structural integrity of tissues and regulating cellular processes such as development, differentiation, and morphogenesis. Cadherin-6 is specifically expressed in the proximal tubules of normal human kidneys, and suggests that changes in cadherin-6 expression are associated with the progression of renal cell carcinoma. In addition, Cadherin 6 is expressed on the platelet surface and plays an essential role in thrombosis in vivo^[1][2].

Rat

HEK293

C-His

EDL82944 (T19-A615)

/

Approximately 67.9 kDa.

Greater than 80% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.