Carboxypeptidase A4/CPA4 Protein, Mouse (HEK293, His)

Carboxypeptidase A4 (CPA4) protein is a metalloprotease associated with the histone hyperacetylation pathway, suggesting a possible involvement in epigenetic regulation. CPA4 is specific for C-terminal amino acids (such as -Phe, -Leu, -Ile, -Met, -Tyr, and -Val) and can selectively cleave substrates, suggesting a role in regulating protein composition and function. Carboxypeptidase A4/CPA4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase A4/CPA4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Carboxypeptidase A4/CPA4 Protein, Mouse (HEK293, His) is 404 a.a., with molecular weight of ~50.0 kDa.

Carboxypeptidase A4 (CPA4) Protein, classified as a metalloprotease, is implicated in the histone hyperacetylation pathway, suggesting a potential role in epigenetic regulation. This enzyme demonstrates specificity in cleaving C-terminal amino acids, with a preference for residues such as -Phe, -Leu, -Ile, -Met, -Tyr, and -Val. The substrate selectivity of CPA4 hints at its involvement in modulating the composition and function of proteins through targeted cleavage. The nuanced enzymatic activity of CPA4 underscores its potential significance in cellular processes associated with histone modification and protein turnover.

Mouse

HEK293

C-6*His

Q6P8K8 (G17-Y420)

71791  [NCBI]

GRDKFFGDQVFRINVRNGDEIRKLTELVNSDHLKLSVWKSPSTFDRPVDILVPSVSLLPVKSFLKSQGLDYSVTIEDLQALLDNEDEEMQHNEGIERSGDFNYGAYHPLEAIYHEMDSIATDFPELVSRVKIGETFEKRPMYVLKFSTGGGKKRPAIWLNAGIHAREWISQATAIWTARKIVTDYKKDPAITSILKKVDIFLLPVANPDGYVYTQSQNRLWRKTRSRNPGSRCVGADPNRNWNASFAGEGTSDNPCSEVYHGSHPNSEVEVKSVVDFIQKHGNFKCFIDLHSYSQLLMYPYGYTVKKAPDAEELDDVARNAAQALASLSGTKYRVGPTCTTVYPASGSSVDWAYDNGIKYAFTFELRDTGYYGFLLPASQIIPTAEETWLGLKTIMEHVRDHLY

Approximately 50.0 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.