CD27/TNFRSF7 Protein, Human (Biotinylated, HEK293, Fc-Avi)

The CD27/TNFRSF7 protein is a receptor for CD70/CD27L and may ensure the survival of activated T cells, suggesting that it plays a crucial role in immune responses. Its association with SIVA1 suggests a regulatory function in the apoptotic pathway. CD27/TNFRSF7 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of CD27/TNFRSF7 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 173 a.a., with molecular weight of ~47.8 kDa.

CD27/TNFRSF7 Protein, serving as the receptor for CD70/CD27L, potentially plays a critical role in the survival of activated T-cells, implicating its involvement in immune responses. Additionally, it may contribute to apoptosis through its association with SIVA1, suggesting a regulatory function in programmed cell death pathways. Existing as a homodimer, CD27/TNFRSF7 interacts with key proteins such as SIVA1 and TRAF2, indicating its engagement in intricate signaling cascades. The multifaceted roles of CD27/TNFRSF7 in T-cell survival and apoptosis underscore its significance in immune regulation and highlight its potential as a target for therapeutic interventions aimed at modulating immune responses.

Human

HEK293

C-Avi;C-hFc

P26842 (A20-I192)

939  [NCBI]

Approximately 47.8 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.