CD27 - CD27 molecule Gene

Also Known as T14; S152; Tp55; TNFRSF7; S152. LPFS2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 939

About CD27

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,444,955-6,451,713 (from NCBI)

This gene has 2 transcripts (splice variants), 545 orthologues, 21 paralogues and is associated with 2 phenotypes. Broad expression in lymph node (RPKM 38.5), spleen (RPKM 21.6) and 14 other tissues.

Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the Apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

CD27 Products (7)

mRNA	Protein	Name
NM_001242.5	NP_001233.2	CD27 antigen isoform b precursor
NM_001413263.1	NP_001400192.1	CD27 antigen isoform a precursor
NM_001413264.1	NP_001400193.1	CD27 antigen isoform c precursor
NM_001413265.1	NP_001400194.1	CD27 antigen isoform d precursor
NM_001413266.1	NP_001400195.1	CD27 antigen isoform e
NM_001413267.1	NP_001400196.1	CD27 antigen isoform e
NM_001413268.1	NP_001400197.1	CD27 antigen isoform e

CD27 Protein Structure

TNFR_c6

0
100
200
260 a.a.

Protein Preferred Names	Protein Names
CD27 antigen	CD27L receptor

CD27 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CD27	P26842	TRAF2	Homo sapiens	Q12933	Anti Tag CoIP	33961781
Intra	CD27	P26842	TRAF2	Homo sapiens	Q12933	Y2H	9692890
Intra	CD27	P26842	CIB1	Homo sapiens	Q99828	Validated Y2H	32296183
Intra	CD27	P26842	CIB1	Homo sapiens	Q99828	Y2H Array	32296183
Intra	CD27	P26842	CIB1	Homo sapiens	Q99828	Y2H Prey Pooling	32296183
Intra	CD27	P26842	SIVA1	Homo sapiens	O15304	Y2H	9177220
Intra	CD27	P26842	SIVA1	Homo sapiens	O15304	Y2H	16683188
Intra	CD27	P26842	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	CD27	P26842	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	CD27	P26842	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD27 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72742	CD27/TNFRSF7 Protein, Human (HEK293, His-Fc)	P26842 (T21-I192)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P75630	CD27/TNFRSF7 Protein, Human (Biotinylated, HEK293, Fc-Avi)	P26842 (A20-I192)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P75632	CD27/TNFRSF7 Protein, Human (sf9, His)	P26842 (A20-I192)	≥ 85%, as determined by reducing SDS-PAGE.
HY-P75633	CD27/TNFRSF7 Protein, Human (Biotinylated, sf9, His)	P26842 (A20-I192)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P75634	CD27/TNFRSF7 Protein, Human (HEK293, Fc)	P26842 (A20-I192)	≥ 95%, as determined by reducing SDS-PAGE.

CD27 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81533	CD27 Antibody (YA1278)	IHC-P	Human
HY-P81533A	CD27 Antibody (YA1278)(PBS only)	IHC-P	Human
HY-P84981	CD27 Antibody (YA4673)	FC, ELISA	Human
HY-P85815	CD27 Antibody (YA5507)	WB, ICC/IF, ELISA	Human
HY-P85859	CD27 Antibody (YA5551)	FC, ELISA	Human

Related Diseases

Diseases	Alias
Lymphoproliferative Syndrome 2	Cd27 Deficiency LPFS2 Combined Immunodeficiency Due To Cd27 Deficiency Autosomal Recessive Lymphoproliferative Disease Due To Cd27 Deficiency
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Combined T And B Cell Immunodeficiency
Lymphoproliferative Syndrome	Lymphoproliferative Disorder Lymphoproliferative Disorders Lymphoproliferative Disorders, Susceptibility To
Common Variable Immunodeficiency	Cvid Common Variable Agammaglobulinemia Common Variable Immune Deficiency Acquired Hypogammaglobulinemia Hypogamma-Globulinemia, Acquired Idiopathic Immunoglobulin Deficiency Primary Antibody Deficiency Primary Hypogammaglobulinemia Acquired Agammaglobulinemia Sporadic Hypogammaglobulinemia Common Variable Hypogamma-Globulinemia Immunoglobulin Deficiency, Late-Onset Common Variable Hypogammaglobulinemia Immunodeficiency, Common Variable
Pars Planitis	Posterior Cyclitis Vitritis Intermediate Uveitis Peripheral Retinal Inflammation Uveitis, Intermediate
Tetanus	Lockjaw Clostridial Tetanus Infection Due To Clostridium Tetani Lock-Jaw
Myelitis	Spinal Cord Inflammation Nos Radiculomyelitis Nos Myeloradiculitis
Neuromyelitis Optica	Devic Disease Devic Syndrome Neuromyelitis Optica Spectrum Disorder Devic'S Disease Devic'S Syndrome Devic'S Neuromyelitis Optica Nmo Nmo Spectrum Disorder Neuromyelitis Optica Spectrum Disorders Devic Neuromyelitis Optica Optic-Spinal Ms Opticospinal Ms Nmosd Opticospinal Multiple Sclerosis Devic Ophthalmoneuromyelitis Optic Neuromyelitis Optic Neuroencephalomyelopathy Nmo - [Neuromyelitis Optica] Optic Neuritis With Demyelination
Hemophagocytic Lymphohistiocytosis	Lymphohistiocytosis, Hemophagocytic Haemophagocytic Syndrome Lymphohistiocytosis Hemophagocytic Hemophagocytic Syndrome Familial Hemophagocytic Lymphocytosis Histiocytoses Of Mononuclear Phagocytes Haemophagocytic Lymphohistiocytosis Nos
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Cryoglobulinemia	Cryoimmunoglobulinaemia
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
Granulomatosis With Polyangiitis	GPA Wegener Granulomatosis Wegener Granulomatosis, Formerly Midline Granulomatosis Wg, Formerly Necrotizing Respiratory Granulomatosis Wg Wegeners Granulomatosis Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis
Cd40 Ligand Deficiency	X-Linked Hyper Igm Syndrome Hyperimmunoglobulin M Syndrome Higm1 Hyper-Igm Syndrome Type 1 X-Linked Hyper-Igm Syndrome Xhigm Higmx-1 X-Linked Hyper-Igm Immunodeficiency Hyper-Igm Syndrome 1 Immunodeficiency With Hyper-Igm, Type 1 Hyper-Igm Syndrome Due To Cd40 Ligand Deficiency Hyper-Igm Syndrome Due To Cd40l Deficiency Hyper-Igm Immunodeficiency Syndrome Hyper-Igm Immunodeficiency Syndrome, Type 1
Transient Hypogammaglobulinemia Of Infancy	Immunoglobulin Maturational Delay Thi - [Transient Hypogammaglobulinaemia Of Infancy]
Macroglobulinemia	Primary Macroglobulinemia Waldenstrom Macroglobulinemia
Transient Hypogammaglobulinemia
B Cell Deficiency	Immunoglobulin Heavy Chain Deficiency B Cell Deficiencies Immunoglobulin Heavy Chain Deletion Humoral Immune Defect
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Digeorge Syndrome	Chromosome 22q11.2 Deletion Syndrome DGS Hypoplasia Of Thymus And Parathyroids Third And Fourth Pharyngeal Pouch Syndrome 22q11.2 Deletion Syndrome Digeorge Sequence Digeorge'S Syndrome Pharyngeal Pouch Syndrome Di-George Syndrome Shprintzen Syndrome
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Immunodeficiency 14	Activated Pi3k-Delta Syndrome Apds Pasli Disease Imd14 Senescent T-Cells-Lymphadenopathy-Immunodeficiency Syndrome Due To P110delta-Activating Mutation P110 Delta-Activating Mutation Causing Senescent T Cells, Lymphadenopathy, And Immunodeficiency
Plasmacytoma	Solitary Plasmacytoma Solitary Myeloma Myeloma - Solitary Myeloma, Solitary Plasmacytoma - Category Solitary Osseous Plasmacytoma Solitary Plasmacytoma Without Mention Of Remission Localised Malignant Plasma Cell Tumour Nos Plasmacytoma Nos
Igg4-Related Disease	Multifocal Fibrosclerosis Igg4-Related Sclerosing Disease Igg4-Related Systemic Disease Immunoglobulin G4-Related Sclerosing Disease Hyper-Igg4 Disease Igg4-Associated Disease Igg4-Positive Multiorgan Lymphoproliferative Syndrome Igg4-Related Autoimmune Disease Igg4-Related Systemic Sclerosing Disease Igg4-Syndrome Multifocal Idiopathic Fibrosclerosis Systemic Igg4-Related Plasmacytic Syndrome Systemic Igg4-Related Sclerosing Syndrome Mediastinal Fibrosis, Familial Retroperitoneal Fibrosis, Familial Igg4-Rd
Immunodeficiency With Hyper-Igm, Type 1	Immunodeficiency, X-Linked, With Hyper-Igm Hyper Igm Syndrome HIGM1 Xhim Hyper-Igm Syndrome Higm Hyper-Igm Syndrome 1 Immunodeficiency 3 Imd3 Immunodeficiency With Hyper-Igm Immunodeficiency With Hyper Igm Type 1 Ihis X-Linked Hyper Igm Syndrome Hyper-Igm Immunodeficiency, X-Linked Hyper Igm Immunodeficiency, X-Linked Hyper Igm Syndrome 1 X-Linked Immunodeficiency With Hyper-Igm 1 Immunodeficiency, With Hyper Igm Immunodeficiency, With Hyper Igm, Type 1 Hyper-Igm Immunodeficiency Syndrome, Type 1 Hyperimmunoglobulin M Syndrome
Immunodeficiency 16	Combined Immunodeficiency Due To Ox40 Deficiency IMD16 Ox40 Deficiency Combined Immunodeficiency With Childhood-Onset Kaposi Sarcoma Combined Immunodeficiency With Impaired Immunity To Hhv-8 Combined Immunodeficiency With Impaired Immunity To Human Herpes Virus 8 Immunodeficiency, Type 16
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Immunodeficiency With Hyper-Igm, Type 4	HIGM4 Hyper-Igm Syndrome Type 4 Immunodeficiency With Hyper-Igm Type 4 Hyper-Igm Syndrome 4 Immunodeficiency With Hyper Igm Type 4 Hyper Igm Syndrome 4 Immunodeficiency, With Hyper Igm, Type 4
Lymphoid Interstitial Pneumonia	Lymphocytic Interstitial Pneumonia Lip Disease Lip Diseases LIP Disease Of Lips
Immunoglobulin Alpha Deficiency	Iga Deficiency Gamma-A-Globulin Deficiency Immunoglobulin A Deficiency
Chickenpox	Varicella Varicella Nos
T Cell Deficiency	T Cell Immunodeficiency T Lymphocyte Deficiency T Lymphocyte Immunodeficiency T-Lymphocyte Deficiency
Selective Immunoglobulin Deficiency Disease
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Potocki-Shaffer Syndrome	Proximal 11p Deletion Syndrome Chromosome 11p11.2 Deletion Syndrome Pss 11p11.2 Deletion P11pds Defect11 Syndrome Deletion Of Chromosome 11p11.2 POSHS
Lymphoplasmacytic Lymphoma	Waldenstrom Macroglobulinemia Malignant Lymphoma - Lymphoplasmacytic Waldenström Macroglobulinaemia Waldenström Macroglobulinaemia Without Mention Of Remission Idiopathic Macroglobulinaemia Primary Macroglobulinaemia
Monoclonal Gammopathy Of Uncertain Significance	Monoclonal Gammopathy Of Undetermined Significance Mgus Mgus - [Monoclonal Gammopathy Of Undetermined Significance] Monoclonal Gammopathy Nos Iga Gammopathy Monoclonal Gammoglobulinopathy
Asymmetric Motor Neuropathy
Anemia, Autoimmune Hemolytic	Autoimmune Hemolytic Anemia Idiopathic Autoimmune Hemolytic Anemia Immuno-Hemolytic Anemia Anemia, Hemolytic, Autoimmune Autoimmune Haemolytic Anaemia Autoimmune Hemolytic Anaemia Acquired Autoimmune Hemolytic Anemia Anemia Hemolytic Autoimmune Familial Auto-Immune Hemolytic Anemia Aha Aiha
Autoimmune Disease Of Exocrine System
Sarcoidosis 1	Sarcoidosis Boeck Sarcoid Besnier-Boeck-Schaumann Disease SS1 Sarcoidosis, Susceptibility To, 1 Lymphogranulomatosis Hodgkin Disease Boeck'S Disease Boeck'S Sarcoid Schaumann'S Disease Or Syndrome Hutchinson-Boeck Disease Or Syndrome
Hypersensitivity Reaction Type Iv Disease	Immunoproliferative Disorders Immunoproliferative Disease
Herpangina	Vesicular Pharyngitis
Pfeiffer Syndrome	Infectious Mononucleosis Acs5 Craniofacial-Skeletal-Dermatologic Dysplasia Acs V Noack Syndrome Gammaherpesviral Mononucleosis Acrocephalosyndactyly Type 5 Pfeiffer Syndrome Type 3 Acrocephalosyndactyly, Type V Glandular Fever Pfeiffer Type Acrocephalosyndactyly Pfeiffer Syndrome Type 2 Acrocephalosyndactylia Type V Filatov'S Disease Monocytic Angina Mononucleosis Pfeiffer'S Disease Acsv Acrocephalosyndactyly, Type 5 Craniofacial-Skeletal-Dermatologic Syndrome Pfeiffer Syndrome Type 1 Classic Pfeiffer Syndrome PS Pfeiffer Syndrome Variant Dysplasia, Craniofacial-Skeletal-Dermatologic Pfeiffer Kissing Disease Infectious Adenitis Pfeiffer Disease
Pediculus Humanus Corporis Infestation	Body Louse Infestation Pediculus Corporis Pediculus Humanus Infestation
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Primary Bacterial Infectious Disease
Refractory Plasma Cell Neoplasm
Disseminated Eosinophilic Collagen Disease
Bronchiectasis 1
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Solid Adenocarcinoma With Mucin Production
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-185483	AMG-172	Inhibitor	/	Phase 1

Inhibitory Antibodies (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99014	Cusatuzumab	Inhibitor	98.87%	Phase 2
HY-P990018	Boserolimab		99.00%	Phase 2
HY-P99057A	Varlilumab (anti-CD27)	Inhibitor	99.68%	Phase 2
HY-P991063	GEN-1053	Inhibitor	99.72%	Phase 2

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-113512	17-HDHA	Inhibitor	98.86%	Unkown
HY-159886	MG-C-30	Agonist	95.55%	Unkown
HY-120255	17(R)-HDHA		98.0%	Unkown
HY-RS02216	CD27 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS16844	Cd27 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23285	Cd27 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99057	Varlilumab	Inhibitor	96.09%	Unkown
HY-P990280	Anti-Mouse CD27 Antibody (RM27-3E5)	Inhibitor	/	Unkown
HY-P990528	Anti-TNFRSF7/CD27 Antibody	Inhibitor	/	Unkown
HY-P991465	Anti-CD27 Antibody (M2177)	Inhibitor	/	Unkown
HY-P991466	Anti-CD27 Antibody (M2191)	Inhibitor	/	Unkown
HY-P991661	AMG-172 Antibody		/	Unkown
HY-P991809	Anti-Mouse CD70 Antibody (TAN 1-7)	Inhibitor	/	Unkown
HY-P99014A	Cusatuzumab (FUT8-KO)	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CD27	VGNC	VGNC:60601
Canis familiaris	CD27	VGNC	VGNC:38941
Bos taurus	CD27	VGNC	VGNC:27018
Mus musculus	CD27	MGD	MGI:88326
Rattus norvegicus	CD27	RGD	RGD:1560499
Others	CD27	NCBI