CD27 Antibody (YA1278)
(Synonyms: CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55)CD27 Antibody (YA1278) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD27.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.118.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
CD27 Antibody (YA1278) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD27.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 55 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 29 kDa
A synthesized peptide derived from human CD27
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.118.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cluster of differentiation 27 (CD27, also TNFRSF7), a co-stimulatory receptor, is a transmembrane phosphoglycoprotein which is expressed on naive T-cells, memory B-cells, natural killer (NK) -cells, and hematopoietic stem cells (HSCs) and progenitor cell.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Found in most T-lymphocytes. -
Subunit
Homodimer (PubMed:1655907, PubMed:34419446). Interacts with SIVA1; may play a role in apoptosis through association with SIVA1 (PubMed:9177220). Interacts with TRAF2 (PubMed:38354704, PubMed:9692890). Interacts ith PTPN6 (PubMed:38354704)
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SwissProt ID
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Synonyms
CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55
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Research Field
Immunology
Documentation