AMG-172 Antibody
AMG-172 Antibody is an anti-CD27L antibody. AMG-172 Antibody can be used for synthesis of ADC AMG-172 (HY-185483).
For research use only. We do not sell to patients.
- CAS No.: 1607838-85-6
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human IgG1 kappa
Human
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TNFRSF7 |
AMG-172 Antibody binds native CD27L with subnanomolar affinity, is internalized into CD27L-expressing cells[1].
AMG-172 Antibody can be used to synthesize ADC AMG-172, which inhibits microtubule function, induces metaphase arrest and exhibits antitumor
activity in preclinical models[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 1607838-85-6
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SMILES
N/A
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMG-172 Antibody Related Classifications
HY-P991661 Related Classifications
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- AMG-172 Antibody
- 1607838-85-6
- ADC Antibodies
- TNF Receptor
- Transmembrane Glycoprotein
- metaphase arrest
- CD27L-expressing cells
- MCC
- microtubule assembly/disassembly dynamics
- CD27L
- relapsed/refractory clear cell renal cell carcinoma
- immunoglobulin G1 monoclonal antibody
- maytansine derivative DM1
- Inhibitor
- inhibitor
- inhibit