CD27/TNFRSF7 Protein, Rat (HEK293, Fc)

The CD27/TNFRSF7 protein is predicted to have endopeptidase inhibitor activity, be ethanol responsive, and be membrane localized. Its ortholog of human CD27 has been implicated in lymphoproliferative syndrome 2, emphasizing immune system regulation. CD27/TNFRSF7 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD27/TNFRSF7 Protein, Rat (HEK293, Fc) is 183 a.a., with molecular weight of ~45 kDa.

CD27/TNFRSF7 Protein is predicted to exhibit cysteine-type endopeptidase inhibitor activity involved in the apoptotic process and is involved in the cellular response to ethanol. This protein is primarily located in the membrane. The human ortholog(s) of this gene are implicated in lymphoproliferative syndrome 2, highlighting its role in immune system regulation. As the orthologous counterpart to human CD27 (CD27 molecule), CD27/TNFRSF7 demonstrates biased expression, with significant levels observed in the Thymus (RPKM 187.5), Spleen (RPKM 34.1), and one other tissue. This expression pattern underscores its potential involvement in immune functions, particularly within lymphoid tissues, and suggests a specialized role in modulating apoptotic processes in response to specific stimuli like ethanol.

Rat

HEK293

C-hFc

NP_001019506 (M1-R183)

500318  [NCBI]

Approximately 45 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.