Cd27 - CD27 molecule Gene

Also Known as Tnfrsf7

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 500318

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in response to ethanol. Located in membrane. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2. Orthologous to human CD27 (CD27 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd27 Products (1)

mRNA Protein Name
NM_001024335.1 NP_001019506.1 CD27 antigen precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to ethanol IEP
IEP: Inferred from expression pattern
16698589 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD27 antigen

  • CD antigen 27

  • tumor necrosis factor receptor superfamily, member 7

Recombinant Cd27 Proteins

Cat. No. Product Name Accession Purity
HY-P75427 CD27/TNFRSF7 Protein, Rat (HEK293, Fc) Q501W2/NP_001019506 (T21-R183) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-185483 AMG-172 Inhibitor / Phase 1
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99014 Cusatuzumab Inhibitor 98.87% Phase 2
HY-P990018 Boserolimab 99.00% Phase 2
HY-P99057A Varlilumab (anti-CD27) Inhibitor 99.68% Phase 2
HY-P991063 GEN-1053 Inhibitor 99.72% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159886 MG-C-30 Agonist 95.55% Unkown
HY-120255 17(R)-HDHA 98.0% Unkown
HY-RS02216 CD27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16844 Cd27 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23285 Cd27 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99057 Varlilumab Inhibitor 96.09% Unkown
HY-P990280 Anti-Mouse CD27 Antibody (RM27-3E5) Inhibitor / Unkown
HY-P990528 Anti-TNFRSF7/CD27 Antibody Inhibitor / Unkown
HY-P991465 Anti-CD27 Antibody (M2177) Inhibitor / Unkown
HY-P991466 Anti-CD27 Antibody (M2191) Inhibitor / Unkown
HY-P991661 AMG-172 Antibody / Unkown
HY-P991809 Anti-Mouse CD70 Antibody (TAN 1-7) Inhibitor / Unkown
HY-P99014A Cusatuzumab (FUT8-KO) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd27 NCBI NCBI:939