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  3. Fibromodulin Protein, Human (HEK293, hFc)

Fibromodulin is an important regulatory protein that affects fiber formation rate and plays a crucial role in collagen fiber formation. It binds type I and type II collagen, affects fibril formation and organization, and contributes to the structural integrity of the extracellular matrix. Fibromodulin Protein, Human (HEK293, hFc) is the recombinant human-derived Fibromodulin protein, expressed by HEK293 , with C-hFc labeled tag.

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제품 설명

Fibromodulin is an important regulatory protein that affects fiber formation rate and plays a crucial role in collagen fiber formation. It binds type I and type II collagen, affects fibril formation and organization, and contributes to the structural integrity of the extracellular matrix. Fibromodulin Protein, Human (HEK293, hFc) is the recombinant human-derived Fibromodulin protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Fibromodulin Protein, a crucial regulator, influences the rate of fibril formation and is implicated in collagen fibrillogenesis, potentially playing a primary role in this process. Known to bind both type I and type II collagen, Fibromodulin exerts its impact on the formation and organization of fibrils, contributing to the structural integrity of the extracellular matrix. Its interactions with various collagen types underline its significance in modulating fibrillogenesis and maintaining the architecture of connective tissues, highlighting its pivotal role in the extracellular matrix dynamics.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q06828/NP_002014.2 (Q19-I376)

Gene ID
Molecular Construction
N-term
Fibromodulin (Q19-I376)
Accession # Q06828/NP_002014.2
hFc
C-term
Protein Length

Full Length of Mature Protein

Synonyms
Fibromodulin; FM; FMOD; KSPG fibromodulin; SLRR2E
AA Sequence

QYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI

Predicted Molecular Mass
68.2 kDa
분자량

Approximately 70 kDa, based on SDS-PAGE under reducing conditions.

Glycosylation
Yes
Purity

≥ 90%, as determined by reducing SDS-PAGE.

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

선적

Shipping with dry ice.

각종 서류
References

Fibromodulin Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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상품명:
Fibromodulin Protein, Human (HEK293, hFc)
Cat. No.:
HY-P75186
수량:
MCE Japan Authorized Agent: