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gdf-7-protein-mouse

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  • HY-P74127
    GDF-8 Protein, Mouse (HEK293, Fc)

    Growth/differentiation factor 8; gdf-8; Myostatin; MSTN

    		 Mouse HEK293
    The GDF-8 protein, also known as myostatin, negatively regulates skeletal muscle growth. It acts as a disulfide-linked homodimer and inhibits its activity by interacting with WFIKKN2. Additionally, it interacts with FSTL3. GDF-8 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived GDF-8 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of GDF-8 Protein, Mouse (HEK293, Fc) is 109 a.a., with molecular weight of ~45 kDa.
  • HY-P77945
    GDF-15 Protein, Mouse (HEK293, Fc)

    gdf-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; gdf15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta

    		 Mouse HEK293
    Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor β (TGF-β) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-β (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCγ). GDF-15 Protein, Mouse (HEK293, Fc) has 115 amino acids expressed by HEK293 cells with N-terminal hFc tag.
  • HY-P700293
    GDF-15 Protein, Mouse (HEK293, His-Flag)

    Growth Differentiation Factor 15; Macrophage inhibitory cytokine 1; gdf-15; MIC-1; NAG-1; PLAB; PTGFB; gdf15; Sbf

    		 Mouse HEK293
    GDF-15 Protein regulates food intake, energy balance, and body weight by binding to its receptor, GFRAL. This activates GFRAL-expressing neurons in the brainstem, triggering a 'emergency circuit' in the parabrachial nucleus and central amygdala during stress. GDF-15 also inhibits growth hormone signaling on hepatocytes and forms a disulfide-linked homodimer. Interacting with GFRAL, it acts as a ligand, facilitating GDF15 internalization and signaling through RET. GDF-15 Protein, Mouse (HEK293, His-Flag) is the recombinant mouse-derived GDF-15 protein, expressed by HEK293, with N-8*His, N-Flag labeled tag. The total length of GDF-15 Protein, Mouse (HEK293, His-Flag) is 115 a.a., with molecular weight of 14-16 kDa.
  • HY-P77946
    GDF-15 Protein, Mouse (Biotinylated, HEK293, Fc)

    gdf-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; gdf15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta

    		 Mouse HEK293
    Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor β (TGF-β) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-β (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCγ). GDF-15 Protein, Mouse (Biotinylated, HEK293, Fc) has 115 amino acids expressed by HEK293 cells with N-terminal hFc tag.
  • HY-P77580
    BMP-9/GDF-2 Protein, Mouse (HEK293, Fc)

    gdf-2; BMP-9; gdf2; BMP9

    		 Mouse HEK293
    The BMP-9/GDF-2 protein is a potent inhibitor of angiogenesis that signals through AVRL1, and endoglin/ENG is required for SMAD1 signaling in endothelial cells. As a homodimer with a disulfide-linked structure, BMP-9/GDF-2 forms a complex with AVRL1, BMPR2, and ACVR2B, which is critical for its signaling cascade. BMP-9/GDF-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived BMP-9/GDF-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BMP-9/GDF-2 Protein, Mouse (HEK293, Fc) is 110 a.a., with molecular weight of 47-50 kDa.
  • HY-P75788
    BMP-3B/GDF10 Protein, Mouse (HEK293, Fc)

    Growth/differentiation factor 10; gdf-10; Bone morphogenetic protein 3B; BMP-3B

    		 Mouse HEK293
    Bone morphogenetic protein 3 (BMP-3; GDF10) is a polymorphic ligand protein belonging to the TGF-β family. BMP-3 is the main component of osteoblast and has osteogenic activity. BMP-3 plays an inhibitory role in the carcinogenic process, and inhibits the occurrence of colon tumors through ActRIIB/ SMad2-dependent and TAK1/JNK signaling pathways. BMP-3B/GDF10 Protein, Mouse (HEK293, Fc) has a total length of 110 amino acids (Q367-R476), is expressed in HEK293 cells.
  • HY-P79333
    BMP-13/GDF-6 Protein, Mouse

    Growth/differentiation factor 6; gdf6; gdf-6; Bone morphogenetic protein 13; BMP-13; Growth/differentiation factor 16; Growth Differentiation Factor 6

    		Mouse E. coli
    The BMP-13/GDF-6 protein is a multifunctional growth factor that plays a critical role in retinal development, control of apoptosis, and dorsoventral positional information. It is critical for bone and joint development in various anatomical regions, influencing species-specific skeletal changes and contributing to the evolution of unique anatomical features. BMP-13/GDF-6 Protein, Mouse is the recombinant mouse-derived BMP-13/GDF-6 protein, expressed by E. coli , with tag free. The total length of BMP-13/GDF-6 Protein, Mouse is 120 a.a., with molecular weight of ~13.7 kDa.

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