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  4. NCAM-1/CD56
  5. NCAM-1/CD56 Protein, Cynomolgus (HEK293, His)

NCAM-1/CD56 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P701026
COA Handling Instructions

NCAM-1/CD56 protein is an important cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. It interacts with MDK and forms a complex with SLC39A6 and SLC39A10, complexly regulating NCAM-1 phosphorylation. NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is 699 a.a., with molecular weight of 95-115 kDa.

For research use only. We do not sell to patients.

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20 μg $175 In-stock
50 μg $380 In-stock
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Description

NCAM-1/CD56 protein is an important cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. It interacts with MDK and forms a complex with SLC39A6 and SLC39A10, complexly regulating NCAM-1 phosphorylation. NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is 699 a.a., with molecular weight of 95-115 kDa.

Background

The NCAM-1/CD56 protein takes on a pivotal role as a cell adhesion molecule, participating in neuron-neuron adhesion, neurite fasciculation, and the outgrowth of neurites. It engages in interactions with MDK and forms a complex with SLC39A6, SLC39A10, and itself. This complex intricately regulates NCAM-1 phosphorylation and facilitates its integration into focal adhesion complexes during epithelial-to-mesenchymal transition, as observed in studies. The versatile involvement of NCAM-1 in cell adhesion and signaling processes highlights its significance in mediating complex cellular interactions critical for neuronal development and transitions between epithelial and mesenchymal states.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

XP_005579710.1 (L20-G718)

Gene ID
Molecular Construction
N-term
NCAM-1 (L20-G718)
Accession # XP_005579710.1
His
C-term
Synonyms
N-CAM-1; NCAM-1; NCAM1; CD56; NCAM; MSK39
Molecular Weight

95-115 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution

Formulation

Supplied as a 0.22μm filtered solution of 50mM Tris, 500mM NaCl, pH 8.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
NCAM-1/CD56 Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P701026
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