2. Recombinant Proteins
  3. Receptor Proteins
  4. OSCAR Protein, Human (HEK293, Fc)

OSCAR Protein, Human (HEK293, Fc)

Cat. No.: HY-P78011
Handling Instructions

OSCAR Protein, a key orchestrator in bone biology, crucially regulates osteoclastogenesis, influencing osteoclast differentiation, formation, and maturation. Focused on bones, OSCAR plays a pivotal role in maintaining skeletal homeostasis and structural integrity, contributing to the dynamic equilibrium of bone remodeling. OSCAR Protein, Human (HEK293, Fc) is the recombinant human-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of OSCAR Protein, Human (HEK293, Fc) is 211 a.a., with molecular weight of 60-70 kDa.

For research use only. We do not sell to patients.

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Description

OSCAR Protein, a key orchestrator in bone biology, crucially regulates osteoclastogenesis, influencing osteoclast differentiation, formation, and maturation. Focused on bones, OSCAR plays a pivotal role in maintaining skeletal homeostasis and structural integrity, contributing to the dynamic equilibrium of bone remodeling. OSCAR Protein, Human (HEK293, Fc) is the recombinant human-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of OSCAR Protein, Human (HEK293, Fc) is 211 a.a., with molecular weight of 60-70 kDa.
Background

OSCAR, a key orchestrator in bone biology, emerges as a crucial regulator of osteoclastogenesis, wielding significant influence in the intricate process of osteoclast differentiation. With a bone-specific focus, OSCAR exerts its regulatory prowess to fine-tune the mechanisms governing the formation and maturation of osteoclasts. Through its pivotal role in osteoclastogenesis, OSCAR contributes to the dynamic equilibrium of bone remodeling, playing a crucial part in maintaining skeletal homeostasis and structural integrity.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

Q8IYS5 (D19-N229)
Gene ID
Molecular Construction
N-term
OSCAR (D19-N229)
Accession # Q8IYS5
hFc
C-term
Synonyms
mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613
Molecular Weight

60-70 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

OSCAR Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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