Prolactin R Protein, Mouse (HEK293, His-Fc)

Prolactin R protein serves as a receptor for the anterior pituitary hormone prolactin and significantly interacts with SMARCA1, NEK3, and VAV2. The latter two interactions are prolactin-dependent, emphasizing the role of the receptor in transducing prolactin-induced signals that are critical for multiple physiological processes, particularly in reproduction and lactation. Prolactin R Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived Prolactin R protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of Prolactin R Protein, Mouse (HEK293, His-Fc) is 210 a.a., with molecular weight of 65-70 kDa.

The Prolactin R protein serves as a receptor for the anterior pituitary hormone prolactin. It engages in crucial interactions with SMARCA1, NEK3, and VAV2, with the latter two interactions being prolactin-dependent. These molecular associations underscore the receptor's role in transducing signals triggered by prolactin, a hormone central to various physiological processes, particularly those related to reproduction and lactation. The interactions with SMARCA1, NEK3, and VAV2 highlight the intricate regulatory network that orchestrates cellular responses in a prolactin-dependent manner.

Mouse

HEK293

C-hFc;C-His

Q08501 (Q20-D229)

19116  [NCBI]

65-70 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.