REG-4 Protein, Human (HEK293, Fc)

REG-4, a calcium-independent lectin, exhibits mannose-binding specificity and retains carbohydrate recognition activity even in acidic environments. Its ability to function independently of calcium suggests a robust and versatile lectin activity. REG-4's involvement is suggested in inflammatory and metaplastic responses within the gastrointestinal epithelium, implying a potential role in processes related to inflammation and cellular transformation in the digestive tract. The unique property of maintaining mannose-binding specificity in acidic conditions suggests an adaptability that may contribute to its functional significance in dynamic physiological environments, particularly within the gastrointestinal context. REG-4 Protein, Human (HEK293, Fc) is the recombinant human-derived REG-4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of REG-4 Protein, Human (HEK293, Fc) is 136 a.a., with molecular weight of ~45 kDa.

REG-4, a calcium-independent lectin, exhibits mannose-binding specificity and retains carbohydrate recognition activity even in acidic environments. Its ability to function independently of calcium suggests a robust and versatile lectin activity. REG-4's involvement is suggested in inflammatory and metaplastic responses within the gastrointestinal epithelium, implying a potential role in processes related to inflammation and cellular transformation in the digestive tract. The unique property of maintaining mannose-binding specificity in acidic conditions suggests an adaptability that may contribute to its functional significance in dynamic physiological environments, particularly within the gastrointestinal context.

Human

HEK293

N-hFc

Q9BYZ8 (D23-P158)

83998  [NCBI]

Approximately 45 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.