1. Recombinant Proteins
  2. CD Antigens
  3. Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  4. CD353/SLAMF8
  5. SLAMF8 Protein, Mouse (HEK293, His)

SLAMF8 Protein, Mouse (HEK293, His)

Cat. No.: HY-P71319
Handling Instructions

SLAMF8 protein may contribute to B-lineage commitment and modulation of B-cell receptor signaling, playing a crucial role in B-cell development and immune responses. Exploring its molecular mechanisms and downstream effects could provide insights into its significance in B-cell biology. SLAMF8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SLAMF8 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF8 Protein, Mouse (HEK293, His) is 211 a.a., with molecular weight of 32-38 kDa.

For research use only. We do not sell to patients.

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Description

SLAMF8 protein may contribute to B-lineage commitment and modulation of B-cell receptor signaling, playing a crucial role in B-cell development and immune responses. Exploring its molecular mechanisms and downstream effects could provide insights into its significance in B-cell biology. SLAMF8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SLAMF8 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF8 Protein, Mouse (HEK293, His) is 211 a.a., with molecular weight of 32-38 kDa.

Background

The SLAMF8 protein emerges as a potential participant in B-lineage commitment, suggesting a role in the developmental processes that guide the differentiation of B-cells. Furthermore, SLAMF8 may be involved in modulating signaling through the B-cell receptor, indicating its influence on crucial cellular pathways associated with B-cell function. The dual potential of SLAMF8 in both B-lineage commitment and the regulation of B-cell receptor signaling underscores its importance in orchestrating key events in B-cell development and immune responses. Further exploration into the specific molecular mechanisms and downstream effects of SLAMF8 in these contexts could provide valuable insights into its functional significance and potential implications for B-cell biology.

Species

Mouse

Source

HEK293

Tag

C-6*His

Accession

Q9D3G2 (V21-D231)

Gene ID

74748  [NCBI]

Molecular Construction
N-term
SLAMF8 (V21-D231)
Accession # Q9D3G2
6*His
C-term
Synonyms
SLAM family member 8; B-lymphocyte activator macrophage expressed; CD353; Slamf8; Blame
AA Sequence

VQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTGGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRWEGTVDFNGEVRSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKD

Molecular Weight

32-38 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SLAMF8 Protein, Mouse (HEK293, His)
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HY-P71319
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