Slamf8 - SLAM family member 8 Gene

Also Known as Blame; SBBI42; 5830408F06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74748

Summary

Enables identical protein binding activity and signaling receptor activity. Involved in B-1 B cell lineage commitment and regulation of B cell differentiation. Acts upstream of or within several processes, including leukocyte chemotaxis involved in inflammatory response; negative regulation of leukocyte migration; and negative regulation of respiratory burst involved in inflammatory response. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLAMF8 (SLAM family member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slamf8 Products (1)

mRNA Protein Name
NM_029084.3 NP_083360.2 SLAM family member 8 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
25799045 MGI
enables signaling receptor activity IDA
IDA: Inferred from direct assay
25799045 MGI
Biological Process GO Annotation Evidence References Source
involved in B-1 B cell lineage commitment IDA
IDA: Inferred from direct assay
11313408 MGI
acts upstream of or within cellular response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
22593622 MGI
acts upstream of or within defense response to bacterium IMP
IMP: Inferred from mutant phenotype
22593622 MGI
acts upstream of or within leukocyte chemotaxis involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within negative regulation of dendritic cell chemotaxis IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within negative regulation of macrophage chemotaxis IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within negative regulation of monocyte chemotaxis IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within negative regulation of neutrophil migration IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within negative regulation of respiratory burst involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
25799045 MGI
acts upstream of or within phagosome acidification IMP
IMP: Inferred from mutant phenotype
22593622 MGI
involved in regulation of B cell differentiation IDA
IDA: Inferred from direct assay
11313408 MGI
acts upstream of or within regulation of NAD(P)H oxidase activity IMP
IMP: Inferred from mutant phenotype
22593622 MGI
acts upstream of or within regulation of kinase activity IMP
IMP: Inferred from mutant phenotype
22593622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLAM family member 8

  • B lymphocyte activator macrophage expressed

Recombinant Slamf8 Proteins

Cat. No. Product Name Accession Purity
HY-P71319 SLAMF8 Protein, Mouse (HEK293, His) Q9D3G2 (V21-D231) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12982 SLAMF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18716 Slamf8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25203 Slamf8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slamf8 NCBI NCBI:56833