SLAMF8 - SLAM family member 8 Gene

Homo sapiens

Also known as BLAME; CD353; SBBI42

Gene ID: 56833 | Gene type: protein coding

About SLAMF8

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,826,873-159,837,492 (from NCBI)

This gene has 4 transcripts (splice variants), 102 orthologues and 9 paralogues. Broad expression in appendix (RPKM 13.5), lymph node (RPKM 12.8) and 22 other tissues.

Summary

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008]

SLAMF8 Products(2)

mRNA	Protein	Name
NM_001330741.2	NP_001317670.1	SLAM family member 8 isoform 2
NM_020125.3	NP_064510.1	SLAM family member 8 isoform 1 precursor

Protein Preferred Names

Protein Names

SLAM family member 8

B lymphocyte activator macrophage expressed

Recombinant SLAMF8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71318	SLAMF8 Protein, Human (HEK293, His)	Q9P0V8 (A23-D233)	≥95%
HY-P78925	SLAMF8 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9P0V8 (A23-D233)	≥95%

Related Diseases

Diseases

Alias

Familial Cold Autoinflammatory Syndrome 3

Plaid	Familial Atypical Cold Urticaria
Facu	FCAS3
Antibody Deficiency And Immune Dysregulation, Plcg2-Associated	Plcg2-Associated Antibody Deficiency And Immune Dysregulation
Familial Cold Urticaria With Common Variable Immunodeficiency	Plcg2 Associated Antibody Deficiency And Immune Dysregulation
Antibody Deficiency And Immune Dysregulation Placg2-Associated	Autoinflammatory Syndrome, Cold, Familial, Type 3

Brachydactyly, Type C

Brachydactyly Type C	BDC
Brachydactyly Haws Type	Brachydactyly, Haws Type
Brachydactyly C

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12982	SLAMF8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SLAMF8	VGNC	VGNC:53130
Rattus norvegicus	SLAMF8	RGD	RGD:1306263
Felis catus	SLAMF8	VGNC	VGNC:65178
Mus musculus	SLAMF8	MGD	MGI:1921998
Macaca mulatta	SLAMF8	VGNC	VGNC:77545
Bos taurus	SLAMF8	VGNC	VGNC:34656
Others	SLAMF8	NCBI

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