1. Recombinant Proteins
  2. CD Antigens
  3. Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  4. CD353/SLAMF8
  5. SLAMF8 Protein, Human (HEK293, His)

SLAMF8 Protein, Human (HEK293, His)

Cat. No.: HY-P71318
COA Handling Instructions

SLAMF8 Protein potentially plays a role in B-lineage commitment and/or modulation of B-cell receptor signaling, suggesting involvement in critical processes of B-cell development and function. The precise mechanisms by which SLAMF8 influences these aspects remain areas of interest, emphasizing its potential significance in regulating immune responses and the intricate signaling network governing B-cell activities. SLAMF8 Protein, Human (HEK293, His) is the recombinant human-derived SLAMF8 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF8 Protein, Human (HEK293, His) is 211 a.a., with molecular weight of ~34.0 kDa.

For research use only. We do not sell to patients.

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Description

SLAMF8 Protein potentially plays a role in B-lineage commitment and/or modulation of B-cell receptor signaling, suggesting involvement in critical processes of B-cell development and function. The precise mechanisms by which SLAMF8 influences these aspects remain areas of interest, emphasizing its potential significance in regulating immune responses and the intricate signaling network governing B-cell activities. SLAMF8 Protein, Human (HEK293, His) is the recombinant human-derived SLAMF8 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF8 Protein, Human (HEK293, His) is 211 a.a., with molecular weight of ~34.0 kDa.

Background

The SLAMF8 protein is suggested to potentially play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor, indicating its potential involvement in critical cellular processes related to B-cell development and function. The precise mechanisms by which SLAMF8 influences B-lineage commitment and modulates B-cell receptor signaling remain areas of interest, emphasizing its potential significance in the regulation of immune responses and the intricate network of signaling events governing B-cell activities.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

Q9P0V8 (A23-D233)

Gene ID
Molecular Construction
N-term
SLAMF8 (A23-D233)
Accession # Q9P0V8
6*His
C-term
Synonyms
SLAM family member 8; B-lymphocyte activator macrophage expressed; BCM-like membrane protein; CD353; SLAMF8; BLAME
AA Sequence

AQVLSKVGGSVLLVAARPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRAQLHSNLSLELGPLESGDSGNFSVLMVDTRGQPWTQTLQLKVYDAVPRPVVQVFIAVERDAQPSKTCQVFLSCWAPNISEITYSWRRETTMDFGMEPHSLFTDGQVLSISLGPGDRDVAYSCIVSNPVSWDLATVTPWDSCHHEAAPGKASYKD

Molecular Weight

Approximately 34.0 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLAMF8 Protein, Human (HEK293, His)
Cat. No.:
HY-P71318
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