SLAMF8 Protein, Human (Biotinylated, HEK293, His-Avi)
SLAMF8 Protein potentially plays a role in B-lineage commitment and/or modulation of B-cell receptor signaling, suggesting involvement in critical processes of B-cell development and function. The precise mechanisms by which SLAMF8 influences these aspects remain areas of interest, emphasizing its potential significance in regulating immune responses and the intricate signaling network governing B-cell activities. SLAMF8 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SLAMF8 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
SLAMF8 Protein potentially plays a role in B-lineage commitment and/or modulation of B-cell receptor signaling, suggesting involvement in critical processes of B-cell development and function. The precise mechanisms by which SLAMF8 influences these aspects remain areas of interest, emphasizing its potential significance in regulating immune responses and the intricate signaling network governing B-cell activities. SLAMF8 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SLAMF8 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Background
The SLAMF8 protein is suggested to potentially play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor, indicating its potential involvement in critical cellular processes related to B-cell development and function. The precise mechanisms by which SLAMF8 influences B-lineage commitment and modulates B-cell receptor signaling remain areas of interest, emphasizing its potential significance in the regulation of immune responses and the intricate network of signaling events governing B-cell activities.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-Avi;C-His
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Accession
Q9P0V8-1 (A23-D233)
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Protein Length
Extracellular Domain
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Conjugation
Biotin
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Synonyms
SLAMF8; BCM-Like Membrane Protein; SLAM Family Member 8; B Lymphocyte Activator Macrophage Expressed; BLAME; B-Lymphocyte Activator Macrophage Expressed; SBBI42; CD353 Antigen; CD353
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AA Sequence
AQVLSKVGGSVLLVAARPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRAQLHSNLSLELGPLESGDSGNFSVLMVDTRGQPWTQTLQLKVYDAVPRPVVQVFIAVERDAQPSKTCQVFLSCWAPNISEITYSWRRETTMDFGMEPHSLFTDGQVLSISLGPGDRDVAYSCIVSNPVSWDLATVTPWDSCHHEAAPGKASYKD
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Predicted Molecular Mass
27.1 kDa
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Molecular Weight
Approximately 30-35 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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