TALDO1 Protein, Human (HEK293, His)

The TALDO1 protein plays a key role in cellular metabolism by catalyzing the rate-limiting step in the non-oxidative phase of the pentose phosphate pathway. Multiple studies have shown that it promotes the reversible conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate into erythrose 4-phosphate and β-D-fructose 6-phosphate. TALDO1 Protein, Human (HEK293, His) is the recombinant human-derived TALDO1 protein, expressed by HEK293 , with C-6*His labeled tag.

The TALDO1 protein is a key enzyme in the pentose phosphate pathway, catalyzing the rate-limiting step of the non-oxidative phase. This enzyme facilitates the reversible conversion of sedoheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. By regulating the flow of metabolites through the pentose phosphate pathway, TALDO1 plays a crucial role in generating ribose-5-phosphate and NADPH, essential for nucleotide biosynthesis and cellular redox balance, respectively. Moreover, TALDO1 exhibits additional regulatory functions by altering its subcellular localization between the nucleus and the cytoplasm, suggesting its involvement in the coordination of various metabolic pathways.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

P37837 (M1-K337)

6888  [NCBI]

Full Length

MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK

Approximately 38 kDa, based on SDS-PAGE under reducing conditions.

≥ 95%, as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of 20 mM Tris-HCl, 10% Glycerol, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.