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ULBP2/NKG2DL2 Protein, Human (HEK293, hFc)

製品番号: HY-P701055
取扱説明書 Technical Support

NKG2DL2 Protein activates KLRK1/NKG2D receptor, promoting natural killer cell cytotoxicity. Importantly, it does not bind beta2-microglobulin, confirmed by research findings. ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) is the recombinant human-derived ULBP2/NKG2DL2 protein, expressed by HEK293 , with C-hFc labeled tag.

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容量 在庫状況
50 μg   お問い合わせ  
100 μg   お問い合わせ  

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製品説明

NKG2DL2 Protein activates KLRK1/NKG2D receptor, promoting natural killer cell cytotoxicity. Importantly, it does not bind beta2-microglobulin, confirmed by research findings. ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) is the recombinant human-derived ULBP2/NKG2DL2 protein, expressed by HEK293 , with C-hFc labeled tag.
Background

The NKG2DL2 protein functions by binding to and activating the KLRK1/NKG2D receptor, thereby facilitating natural killer cell cytotoxicity. Its interaction with KLRK1/NKG2D has been documented. Notably, this protein does not exhibit binding affinity to beta2-microglobulin, as indicated by research findings.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

Q9BZM5 (G26-S216)
Gene ID
Molecular Construction
N-term
ULBP2 (G26-S216)
Accession # Q9BZM5
hFc
C-term
Protein Length

Full Length of Mature Protein
Synonyms
ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; RAET1L; ULBP2; ULBP-2/5/6; NKG2D ligand 2
AA Sequence

GRADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLRDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSFDGQIFLLFDSEKRMWTTVHPGARKMKEKWENDKVVAMSFHYFSMGDCIGWLEDFLMGMDSTLEPSAGAPLAMS

Predicted Molecular Mass
48.4 kDa
分子量

Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
純度

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
ドキュメンテーション
取扱説明書 (2659 KB)

ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
ULBP2/NKG2DL2 Protein, Human (HEK293, hFc)
製品番号:
HY-P701055
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