2. Neuronal Signaling
  3. Dopamine Transporter
  4. RTI 336

RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels.

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RTI 336

RTI 336 Chemical Structure

CAS No. : 204069-50-1

Size Prix Stock Quantité
500 μg Obtenir un devis 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
1 mg Obtenir un devis 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
2.5 mg Obtenir un devis 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
5 mg Obtenir un devis 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks
10 mg   Obtenir un devis  
50 mg   Obtenir un devis  
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RTI 336 Related Antibodies

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Description

RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1].

In Vivo

RTI 336 (3 mg/kg; sc; 30 min pretreatment) significantly decreases the number of infusions of addictive agent in Lewis rats[1].
RTI 336 (3 mg/kg; ip; 30 min pretreatment) decreases response rates (lever presses/s) induced by addictive agent in Lewis rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Essai clinique
Masse moléculaire

429.38

Formule

C24H26Cl2N2O
CAS No.
SMILES

CN1[C@H]2[C@@H](C3=CC(C4=CC=C(C)C=C4)=NO3)[C@@H](C5=CC=C(Cl)C=C5)C[C@@H]1CC2.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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RTI 336 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RTI 336204069-50-1RTI336RTI-336Dopamine TransporterDATSLC6A3Inhibitorinhibitorinhibit

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RTI 336
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HY-107055
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