204069-50-1
204069-50-1
Chemical Structure
RTI 336
- CAS No.: 204069-50-1
- Formula:C24H26Cl2N2O
- Molecular Weight:429.38
IUPAC Name: 5-((1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl)-3-(p-tolyl)isoxazole hydrochloride
InChIKey: IZMZEMAKFSYLMD-SXBQIKTFSA-N
SMILES: CN1[C@H]2[C@@H](C3=CC(C4=CC=C(C)C=C4)=NO3)[C@@H](C5=CC=C(Cl)C=C5)C[C@@H]1CC2.Cl
Biological Activity: RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1].
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RTI 336 | RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels. | |||||||||||||||||||||
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