RTI 336
RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels.
For research use only. We do not sell to patients.
- CAS No.: 204069-50-1
- Formula: C24H26Cl2N2O
- Molecular Weight:429.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
RTI 336 (3 mg/kg; ip; 30 min pretreatment) decreases response rates (lever presses/s) induced by addictive agent in Lewis rats[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 204069-50-1
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Molecular Weight 429.38
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Formula C24H26Cl2N2O
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SMILES
CN1[C@H]2[C@@H](C3=CC(C4=CC=C(C)C=C4)=NO3)[C@@H](C5=CC=C(Cl)C=C5)C[C@@H]1CC2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)