2. Neuronal Signaling Membrane Transporter/Ion Channel
  3. Amino Acid Decarboxylase GABA Receptor
  4. L-Allylglycine

L-Allylglycine  (Synonyms: L-2-Allylglycine)

製品番号: HY-W012906 純度: 98.0%
COA 取扱説明書 Technical Support

L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity.

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CAS 番号 : 16338-48-0

容量 価格（税別） 在庫状況 数量
5 g $38 在庫あり
10 g $69 在庫あり
25 g $160 在庫あり
50 g $305 在庫あり
100 g $580 在庫あり
> 100 g   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Allylglycine:

L-Allylglycine 関連抗体

Top Publications Citing Use of Products

    L-Allylglycine purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2022 Dec;298(12):102603.  [Abstract]

    The effect of ACE2-mediated up-regulation of AKT phosphorylation is almost blocked by (S)-2-Allylglycine (Ally) (5 mM; 24 h) in HepG2 cells.

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    製品説明

    L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity[1][2].

    体内実験

    L-Allylglycine (150 mg/kg, ip or 200 μg, intranigral injection, single dose) induces convulsive behaviors in Sprague-Dawley rat models[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Sprague-Dawley rats models[2].
    Dosage: 150 mg/kg or 200 μg
    Administration: ip or intranigral injection, single dose
    Result: Reduced the GABA content in the hippocampus, cortex and cerebellum.
    Induced running fits, partial rigidity, and convulsions in rats.
    分子量

    115.13

    分子式

    C5H9NO2
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    溶剤 & 溶解度
    体外: 

    H2O : 50 mg/mL (434.29 mM; Need ultrasonic)

    DMSO : < 1 mg/mL (insoluble or slightly soluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 8.6858 mL 43.4292 mL 86.8583 mL
    5 mM 1.7372 mL 8.6858 mL 17.3717 mL
    10 mM 0.8686 mL 4.3429 mL 8.6858 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

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    体積 （開始）

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    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: ≥98.0%

    COA (246 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 8.6858 mL 43.4292 mL 86.8583 mL 217.1458 mL
    5 mM 1.7372 mL 8.6858 mL 17.3717 mL 43.4292 mL
    10 mM 0.8686 mL 4.3429 mL 8.6858 mL 21.7146 mL
    15 mM 0.5791 mL 2.8953 mL 5.7906 mL 14.4764 mL
    20 mM 0.4343 mL 2.1715 mL 4.3429 mL 10.8573 mL
    25 mM 0.3474 mL 1.7372 mL 3.4743 mL 8.6858 mL
    30 mM 0.2895 mL 1.4476 mL 2.8953 mL 7.2382 mL
    40 mM 0.2171 mL 1.0857 mL 2.1715 mL 5.4286 mL
    50 mM 0.1737 mL 0.8686 mL 1.7372 mL 4.3429 mL
    60 mM 0.1448 mL 0.7238 mL 1.4476 mL 3.6191 mL
    80 mM 0.1086 mL 0.5429 mL 1.0857 mL 2.7143 mL
    100 mM 0.0869 mL 0.4343 mL 0.8686 mL 2.1715 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    L-Allylglycine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
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      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Allylglycine16338-48-0L-2-AllylglycineAmino Acid DecarboxylaseGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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    製品名:
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    製品番号:
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