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LTA

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  • HY-P74776

    Leukemia inhibitory factor; Leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4H

    Mouse Sf9 insect cells
    LTA4H Protein, a bifunctional zinc metalloenzyme, functions as an epoxide hydrolase, converting leukotriene A4 (LTA4) to pro-inflammatory leukotriene B4 (LTB4). It also acts as an aminopeptidase, cleaving N-terminal arginines and countering inflammation, particularly through Pro-Gly-Pro (PGP) cleavage. LTA4H contributes to resolvin E1 and 18S-resolvin E1 biosynthesis, generating potent anti-inflammatory and pro-resolving lipid mediators. Its multifaceted activities underscore its intricate role in regulating inflammatory processes and lipid mediator biosynthesis. Leukotriene A4 Hydrolase/LTA4H Protein, Mouse (sf9, His) is the recombinant mouse-derived Leukotriene A4 Hydrolase/LTA4H protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of Leukotriene A4 Hydrolase/LTA4H Protein, Mouse (sf9, His) is 611 a.a., with molecular weight of ~62 kDa.

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