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Results for "

17�� hsd3 Inhibitors

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18173
    AZD8329

    		11β-HSD Metabolic Disease
    AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3 .
    AZD8329
  • HY-103394
    TC HSD 21

    		17β-HSD Cancer
    TC HSD 21 is a selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) against related 17β-HSD isozymes, with an IC50 of 14 nM in HeLa cells. TC HSD 21 can be used in the research of prostate cancer .
    TC HSD 21
  • HY-118382
    SCH-451659

    STX1383

    		 17β-HSD Cancer
    SCH-451659 (STX1383) is an orally active, selective 17β-HSD3 inhibitor with an IC50 of 2.4 nM against h17β-HSD3. SCH-451659 selectively blocks the conversion of androstenedione to testosterone. SCH-451659 reduces testosterone levels in mice. SCH-451659 exhibits anticancer activity against androstenedione-dependent prostate tumors .
    SCH-451659
  • HY-112744
    BMS-856

    		17β-HSD Cancer
    BMS-856 is a 17β-HSD3 inhibitor. BMS-856 inhibits enzymatic activity of 17β-HSD3, with IC50s of 60 and 300 nM respectively in the enzyme and whole cell assays .
    BMS-856
  • HY-103394R
    TC HSD 21 (Standard)

    		Reference Standards 17β-HSD Cancer
    TC HSD 21 (Standard) is the analytical standard of TC HSD 21 (HY-103394). This product is intended for research and analytical applications. TC HSD 21 is a selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) against related 17β-HSD isozymes, with an IC50 of 14 nM in HeLa cells. TC HSD 21 can be used in the research of prostate cancer .
    TC HSD 21 (Standard)

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