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4562-36-1

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Natural
Products

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-136933
    Gitoxin

    		Na+/K+ ATPase Cardiovascular Disease
    Gitoxin is a degradation metabolite of Digitoxin (HY-B1357) and a non-competitive Na +/K +-ATPase inhibitor, with an IC50 of 1.18e-6 M against the porcine high-affinity subtype and an IC50 of 2.85e-5 M against the porcine low-affinity subtype. Gitoxin regulates atrial contractility and rhythmicity. Gitoxin is applicable to research related to congestive heart failure .
    Gitoxin
  • HY-136933R
    Gitoxin (Standard)

    		Reference Standards Na+/K+ ATPase Cardiovascular Disease
    Gitoxin (Standard) is the analytical standard of Gitoxin. This product is intended for research and analytical applications. Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably .
    Gitoxin (Standard)

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